Ocular and neural distribution of feline herpesvirus-1 during active and latent experimental infection in cats

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Ocular and neural distribution of feline herpesvirus-1 during active and latent experimental infection in cats

BACKGROUND Herpes simplex virus 1 (HSV-1) and varicella zoster virus (VZV) cause extensive intra-ocular and neural infections in humans and are closely related to Felid herpes virus 1 (FeHV-1). We report the extent of intra-ocular replication and the extent and morphological aspects of neural replication during the acute and latent phases of FeHV-1 infection. Juvenile, SPF cats were inoculated ...

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occurrence of chlamydophila felis, feline herpesvirus 1 and calcivirus in domestic cats of iran

background and objectives: feline herpesvirus-1, feline calicivirus and chlamydophila felis are the main causes of feline upper respiratory tract disease. this study was conducted to identify of fehv-1, fcv and c. felis infections in domestic cat population and also to estimate the prevalence of each specific infection in iran. materials and methods: the ocular conjunctiva and oropharyngeal spe...

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Effect of topical ophthalmic application of cidofovir on experimentally induced primary ocular feline herpesvirus-1 infection in cats.

OBJECTIVE To evaluate the efficacy of twice-daily ophthalmic application of 0.5% cidofovir solution in cats with experimentally induced primary ocular feline herpesvirus-1 (FHV-1) infection. ANIMALS Twelve 6-month-old sexually intact male cats. PROCEDURES Cats were randomly assigned to either a treatment or control group. Ocular infection with FHV-1 was induced (day 0) in all cats via inocu...

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Feline herpesvirus-1: ocular manifestations, diagnosis and treatment options.

PRACTICAL RELEVANCE Feline herpesvirus-1 (FHV-1) is a major cause of feline morbidity. Following exposure to the virus, virtually all cats become persistently infected and many of these will develop recrudescent disease on one or more occasions during their lifetime. Acute ocular herpetic disease manifests as conjunctivitis, corneal ulceration and keratitis, and can be severe and painful. Repea...

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ژورنال

عنوان ژورنال: BMC Veterinary Research

سال: 2013

ISSN: 1746-6148

DOI: 10.1186/1746-6148-9-185